Synvisc Hylan G-F 20 16 mg/ 2 ml, 2 ml x 3 pre-filled syringes


2 ml x 3 pre-filled syringes

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Synvisc Hylan G-F 20 16 mg/ 2 ml, 2 ml x 3 pre-filled syringes

The product should not be used in the event of venous or lymphatic stasis, severe arthritis, joint infections, and skin diseases or infections at the site.


  • Synvisc One Hylan G-F 20 is a preparation intended for use in the periodic replacement and supplementation of synovial fluid in patients at various stages of degenerative changes in the joints.


  • 1 ml of G-F 20 hylan contains: hylan 8.0 mg, sodium chloride 8.5 mg, disodium hydrogen phosphate 0.16 mg, sodium dihydrogen phosphate monohydrate 0.04 mg, water for injections q.s.

How to use

  • The content of the syringe should be used immediately after opening the package; prior to injection of G-F 20 hylan, remove synovial fluid or exudate from the knee; inject at room temperature; to remove the syringe from the blister (or tray), hold the syringe by the body without touching the plunger; administer with the strict observance of the rules of asepsis, with particular care when removing the stopper from the vial; you must twist the gray protective cap before removing it. This will minimize product leakage; when using Synvisc One, use a needle with dimensions of 18-22, depending on the joint into which the medical device will be administered, use a needle of an appropriate length; to ensure tightness and prevent leakage, attach the needle securely during administration while firmly grasping the Luer connector; when attaching the needle or removing its cover, do not over-tighten the needle and apply excessive pressure to it, as this may break the tip of the syringe; the product should be administered only into the synovium, if necessary, with the help of fluoroscopy, especially before administration to the hip or shoulder joint; the contents of the syringe are for single use only.


  • Synvisc hylan A and B were produced on the basis of a highly purified extract of bird origin. Hylans are derivatives of hyaluronate (the sodium salt of hyaluronic acid) that contain the repeating disaccharide units of N-acetyl-glucosamine and sodium glucuronate.

Important tips:

  • Do not administer intravascularly.
  • It should not be administered outside the articular or synovial tissue and joint capsule.
  • The product contains small amounts of proteins of bird origin.
  • Store at +2? up to +30 ?. Do not freeze.

Genzyme Europe;
1125 Pleasant View Terrace Ridgefield,
NJ 07657, USA.

Sanofi Aventisul. Bonifraterska 1700-203 Warsaw

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