Cingal cross-linked hyaluronic acid with triamcinolone hexacetonide as an excipient. Cingal is an off-white, opaque, sterile, single-use solution of cross-linked hyaluronic acid (HA) gel and triamcinolone (TH) hexacetonide (TH), a corticosteroid, as an excipient. Cingal is a biocompatible and non-pyrogenic substance. There is no physical or chemical interaction between the cross-linked hyaluronic acid contained in Cingal and the triamcinolone hexacetonide, because the micronized triamcinolone hexacetonide particles are suspended in the viscoelastic hyaluronic acid gel and remain in the product as a separate solid phase.
An intra-articular injection administered into the synovial cavity of a human joint to relieve the symptoms of osteoarthritis.
The required amount of formulation is injected into the selected joint space using a sterile, disposable hypodermic needle of the appropriate size. A sterile needle must be attached to the syringe containing the preparation. An 18-21 gauge needle is recommended for injection into the knee. Before injecting the preparation, the doctor must make sure that the needle is properly inserted into the synovial space.
Anika Therapeutics, Inc.
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Bedford, MA 01730