Mastelli Plinest Newest (1x2ml) preparation for biorevitalization on the basis of polynucleotides

The product may only be used by professionals.

By making a purchase, you declare that you are a doctor or cosmetologist trained in aesthetic medicine.

  • Composition features: mannitol, polynucleotides
  • Hyaluronic acid concentration: 10 mg/ml


Availability: 26 in stock

Mastelli Plinest Newest (1x2ml) preparation for biorevitalization on the basis of polynucleotides

SKU 11832 Categories ,

The preparation Newest is a unique product developed by the Italian pharmaceutical company Mastelli, which is known in the world as a manufacturer of bioreparations with polynucleotides (PDRN). The combination of hyaluronic acid, PDRN and mannitol provides an immediate revitalizing and rejuvenating effect that lasts for a long time. Damage repair and cell renewal occurs by activating the dermis’s own resources.

Main characteristics of Mastelli Newest, preparation for biorevitalization on the basis of polynucleotides 2 ml

The product for intradermal injections is produced as a transparent sterile gel. The product’s unique properties and high effectiveness are due to its formula. The composition of Newest includes:

  • hyaluronic acid – 10 mg/ml;
  • polynucleotide – 10 mg / ml;
  • mannitol – 200 mmol/l.

Hyaluronic acid – a traditional component of bioreparatives, has a pronounced moisturizing effect, increases skin elasticity and firmness.

PN-HPT – a patented polynucleotide by Mastelli, is a fragment of DNA extracted from the milk of the salmon family of fish.  PDRN is a linear polymer capable of repairing damaged links of cellular DNA. In addition, polynucleotides increase the metabolic activity of fibroblasts and stimulate the synthesis of collagen and other protein structures of the extracellular matrix.

According to laboratory studies conducted by the manufacturing company, hyaluronic acid increases the effectiveness of PN-HPT by 20%. Mannitol enhances and extends the effect of hyaluronic acid by 30%.

All components of the product are well absorbed by the dermal tissues and are absolutely safe for your health.

Bioreparant Mastelli Newest can be purchased in 2 ml syringes. The kit includes 2 needles 30G ½. The price of Mastelli Newest is beneficial both for cosmetologists and their patients, because the effect is prolonged, and there is no need to repeat the procedure earlier than in 2 months.

Application area of Mastelli Newest, preparation for biorevitalization on the basis of polynucleotides 2 ml

The product is intended for intradermal injection in the following areas:

  • face, including the periorbital area;
  • decollete
  • neck;
  • the back of the hands.

Bioreparant is used for:

  • improving the complexion;
  • improving skin firmness and elasticity;
  • smoothing existing wrinkles and preventing the appearance of new wrinkles;
  • hydration of the skin;
  • lifting the facial oval;
  • anti-aging.

Mastelli Newest is suitable for women and men and can be used at any age after 18. The procedure is especially effective for fine wrinkled type of aging, thin and sensitive skin. For body biorevitalization, reducing the appearance of stretch marks Newest One product in ampoules is used.

Procedure protocol

The gel for bioreparation is available for sale only to practicing cosmetologists. The procedure can only be performed by a specialist who has been specially trained to work with the product and has received a certificate confirming their qualifications.

Before injections the skin is cleaned of makeup, dirt and sebum. If the patient is hypersensitive, a local anesthetic in the form of a cream or gel is used. Newest is injected using the following techniques:

  • linear;
  • micropapule;
  • fan;
  • reinforcement technique.

After injections the skin is treated with an antiseptic. To enhance the effect, an anti-age mask can be applied.

The course consists of an average of 3 treatments, which are carried out at intervals of 2-3 weeks. Single maintenance sessions are recommended every 45-60 days.

Result of application

The effect of bioreparation becomes visible after just one injection. The skin looks considerably younger, the face looks healthy and relaxed. Injection marks disappear within 2-4 days.

On the day of the procedure, it is necessary to refrain from touching the injected areas with your hands, or using heavy oily decorative cosmetics. For 2 weeks, it is undesirable to sunbathe on the beach or in a solarium, go to the sauna, have heavy physical activity.


Contraindications for injections Newest are:

  • pregnancy, breastfeeding;
  • individual intolerance to the components of bioreparant;
  • diabetes;
  • blood clotting disorders;
  • autoimmune disorders;
  • dermatitis, dermatoses;
  • tendency to keloid scars.

The procedure is rescheduled if the client is ill with a cold, takes blood thinning medications, has inflammations or wounds in the area of the supposed injections.

Storage and transportation

The preparation is stored in a darkened space away from the sun and heat at +2C +25C. Do not freeze or damage the syringe.

  • Indications for use

    Skin flabbiness
    Fine lines
    Skin sagging
    Dry and flaky skin

  • Composition features


  • Hyaluronic acid concentration

    10 mg/ml

  • Volume (ml)

    2 ml

  • Duration of action

    up to 6 months




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